There may occasionally be complication with reproduction, however untimely ejaculation (PE) may also adversely have an effect on sexual satisfaction, both for men and their partners. 35. Chew KK, Stuckey BG, Earle CM, et al. Penile fibrosis in intracavernosal prostaglandin E1 injection therapy premature ejaculation solutions for erectile dysfunction. Int J Impot Res 1997; 9: 225-229.